Dear Dr. Gott: I am a 53-year-old female who is about 50 pounds overweight. I have saved, for years, the column you wrote on fatty tumours. I had a few of them, but my doctor said to leave them alone, even though they could be seen through my clothing. In the past two to three years, they have multiplied, and I know I probably have hundreds of them. I've had a few removed that are painful, and they were lipomas, as suspected. Some of the remaining ones are painful; some are not.

Should I continue to "let it go", or should I have more removed? In your column, you said it could be associated with Gardner's syndrome. Should I look into that area? Would losing weight help, or would they just become more pronounced?

Reply: Most peripheral nerve tumours are benign. There are a number of types, including lipomas, ganglion cysts, schwannomas, dumbbell tumours and neurofibromas.

Lipomas present as soft lumps under the skin, commonly appearing on the back, neck, arms or shoulders, caused by slow-growing fat cells. As a general rule, they do not cause pain, but because they can compress nerves, you should have periodic exams.

Ganglion cysts can occur almost anywhere but commonly form near the wrist or at the base of a finger. If there's no pain, you can ignore them. If there's pain, restricted use of a joint and paresthesias, surgical removal may be appropriate.

A schwannoma is common, slow-growing, benign and can appear anywhere on the body. Vestibular schwannomas occur near the cerebellum and brainstem. They can press on the nerves that control balance and affect hearing.

Dumbbell tumours are so called because of their appearance. They may occur in the spine or lower abdomen by the hip. They can become intertwined with the sciatic nerve. If surgery is necessary, it should be accomplished at an extremely reputable facility.

Neurofibromas are common in people diagnosed with neurofibromatosis. Most patients have mild symptoms, but related conditions, such as bone enlargement or deformity, scoliosis and tumours affecting the eye, can occur.

Colon polyps, multiple osteoma and soft-tissue tumours characterise Gardner's syndrome. The average age of diagnosis is 22. A common symptom, other than lipomas, is dental anomalies, such as multiple impactions. Treatment depends on the location and appearance of the lesions. Surgical excision may be recommended.

Speak with your physician about a weight-loss program. I don't know whether losing 50 pounds would improve your situation. I do know that fat cells increase in volume and size with weight gain, and liposuction, for example, will reduce the number of fat cells in the body. If losing weight works, you will feel better and the number of slow-growing fat cells within your body may be reduced. This is a win-win situation.

With respect to "leaving them alone", I would buy that approach only if I were convinced all the lesions were benign and that removal, weight loss, liposuction and every other consideration has been ruled out. If you can't get that assurance or other management options from your doctor, request a referral for a second opinion.

To provide related information, I am sending you a copy of my Health Report 'A Strategy for Losing Weight – Introduction to the No Flour, No Sugar Diet'. Other readers who would like a copy should send a self-addressed stamped number ten envelope and a $2 cheque or money order to Newsletter, PO Box 167, Wickliffe, Ohio 44092-0167. Be sure to mention the title or print an order form off my website at www.AskDrGottMD.com.

Dr. Peter H. Gott is a retired physician and the author of several books, including 'Live Longer, Live Better', 'Dr. Gott's No Flour, No Sugar Diet' and 'Dr. Gott's No Flour, No Sugar Cookbook', which are available at most bookstores or online. His website is www.AskDrGottMD.com. Contact him c/o United Media, 200 Madison Avenue, fourth floor, New York, New York 10016.