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Benefits of prenatal vitamin A last decade

BOSTON (Reuters) – Children whose malnourished mothers took vitamin A during pregnancy had stronger lungs throughout childhood, with the benefits measurable well past the age of nine, researchers reported last week.

Lung capacity was about three percent higher in children whose mothers took vitamin A compared to those whose mothers received a placebo, the study of 1,371 children in Nepal showed.

"Early interventions involving vitamin A supplementation in communities where undernutrition is highly prevalent may have long-lasting consequences for lung health," Dr. William Checkley of Johns Hopkins University in Baltimore and colleagues wrote in the New England Journal of Medicine.

When mothers were given beta carotene, a precursor of vitamin A, their children did not score higher on the lung capacity test.

The benefits are believed to have come from treatment during pregnancy because all the children received regular vitamin A supplements after birth.

The researchers said an estimated 190 million preschool-age children and 19 million pregnant women have vitamin A deficiency worldwide. The shortfall can cause health problems during pregnancy and early development, including lung problems.

The study piggybacked off a test done in the 1990s in which 44,646 women in 30 village developments in Nepal were given weekly supplements before, during and after pregnancy.