This weekend will be a challenge for FPL managers as several key assets are not in action, such as Heung-Min Son and Mohamed Salah.

As a result, Aston Villa forward Leon Bailey and Brentford forward Ivan Toney are good replacements but keep an eye on the performances of Manchester United striker Rasmus Hojlund, whose two goals at the weekend made him the youngest player to score in six straight Premier League matches.

Saturday

Aston Villa v Nottingham Forest (11am)

Aston Villa moved back into the final guaranteed Champions League spot with victory at Fulham. Diego Carlos, Ezri Konsa, Tyrone Mings, Emiliano Buendia, Boubacar Kamara and Jhon Duran are out with various injuries this match.

Nottingham Forest pulled five points clear of the relegation zone with a home win over West Ham last week. Gonzalo Montiel and Chris Wood are out with hamstring injuries this week.

Prediction: 2-1

Brighton & Hove Albion v Everton (11am)

Brighton smashed Sheffield United 5-0 last week to keep in touch with the Champions League qualification race. Julio Enciso, Solly March, James Milner, Jack Hinshelwood and Joao Pedro are out for the Seagulls.

Everton jumped out of the bottom three on goal difference after their home draw with Crystal Palace on Monday, scoring their 14th set-piece goal of the season. Andre Gomes, Dele Alli and Arnaut Danjuma are out through injury.

Prediction: 2-0

Crystal Palace v Burnley (11am)

Crystal Palace prepare for their first match under new head coach Oliver Glasner, with Rob Holding, Eberechi Eze, Marc Guehi, Cheick Doucoure, Michael Olise and Jesurun Rak-Sakyi unavailable for selection. Will Hughes is doubtful with a knock.

Burnley were thrashed at home by Arsenal to remain in the danger zone by seven points. Nathan Redmond, Luka Koleosho and Lyle Foster are out with injury this weekend, while Jordan Beyer and Aaron Ramsey are doubtful.

This is an equal rivalry, with each side winning six of their 15 league encounters.

Prediction: 1-1

Manchester United v Fulham (11am)

Manchester United have won five straight games to move within five points of the top four. Tyrell Malacia, Lisandro Martinez, Aaron Wan-Bissaka, Mason Mount and Anthony Martial are out through injury this week, while Luke Shaw is doubtful.

Fulham struggled to get going in the home defeat to Aston Villa, their fifth defeat in their last nine league matches. Joao Palhinha is suspended to yellow card accumulation while Raul Jimenez is out with a hamstring injury this weekend.

Prediction: 2-0

Bournemouth v Manchester City (1.30pm)

Bournemouth are stuttering with one win in seven games, giving up the lead twice at Newcastle in a 2-2 draw at the weekend. Philip Billing is suspended and Ryan Fredericks, James Hill, Max Aarons and Tyler Adams are out with injuries. Romain Faivre is doubtful through illness.

Manchester City edged Brentford in midweek after their home draw with Chelsea last Saturday. Josko Gvardiol is out with an ankle injury, while Jack Grealish is doubtful.

City have won all 13 Premier League meetings with Bournemouth.

Prediction: 1-2

Arsenal v Newcastle United (4pm)

Arsenal have hit their stride in the Premier League but lost to Porto in the Champions League on Wdnesday. Mikel Arteta’s side will be without Jurrien Timber and Thomas Partey , while Takehiro Tomiyasu, Oleksandr Zinchenko, Fabio Vieira and Gabriel Jesus are doubtful.

Newcastle showed strong character to come from behind twice and draw with Bournemouth. Nick Pope, Matt Targett, Joelinton and Callum Wilson are unavailable while Joe Willock, Alexander Isak and Fabian Schar are doubtful

Prediction: 3-1

Sunday

Wolverhampton Wanderers v Sheffield United (9.30am)

Wolves edged Tottenham to maintain slim hopes of another European season. Matheus Cunha is out with a hamstring injury this weekend.

Sheffield United are seven points from safety following the home thumping by Brighton and Mason Holgate is suspended after being sent off in that game. Chris Basham, John Egan, Max Lowe, Rhys Norrington-Davies and Daniel Jebbison are out to injury or illness, while George Baldock, Ben Brereton Diaz and Cameron Archer are doubtful.

Prediction: 2-2

Monday

West Ham United v Brentford (4pm)

West Ham have conceded eleven goals in three straight league defeats. Kalvin Phillips is suspended after being sent off on his second start of a loan spell from Man City, while Lucas Paqueta is doubtful with a calf injury.

Brentford have suffered four defeats in five matches to stay five points above the bottom three. Rico Henry, Aaron Hickey, Ethan Pinnock, Josh Dasilva, Bryan Mbeumo and Kevin Schade are out to various injuries this match.

Brentford have won all five previous meetings with the Hammers.

Prediction: 1-1