With the FA Cup semi-finals being played this weekend, it means that Tottenham amd both Manchester clubs do not have a match this gameweek. Fulham midfielder Andreas Pereira, despite his side having a tricky home fixture against Liverpool, is a strong option for this round of matches after making four goal contributions (two goals and two assists) in his last four league appearances.

Saturday

Luton Town v Brentford (11am)

Luton were comprehensively beaten at Manchester City last week to remain one point from safety.

Mads Juel Andersen, Amari Bell, Gabriel Osho, Dan Potts, Tom Lockyer, Marvelous Nakamba, Elijah Adebayo, Chiedozie Ogbene and Jacob Brown are out with various injuries, while Teden Mengi and Albert Sambi Lokonga are doubtful this week.

Brentford eased past Sheffield United to pull seven points clear of the drop zone. Aaron Hickey, Rico Henry, Ben Mee, Josh Dasilva and Christian Norgaard are out to injury, while Kristoffer Ajer is doubtful.

Prediction: 2-2

Sheffield United v Burnley (11am)

Sheffield United are now ten points from safety after the away defeat to Brentford. George Baldock, Chris Basham, John Egan, Max Lowe, Rhys Norrington-Davies, Tom Davies, Rhian Brewster and Daniel Jebbison are out through injury and illness, while Jayden Bogle and Jack Robinson are doubtful.

Burnley have suffered just one defeat in their last five games but remain six points from safety after the home draw with Brighton. Nathan Redmond, Luca Koleosho and Aaron Ramsey will miss this crucial battle through injury, while Ameen Al-Dahkil, Jordan Beyer, Han-Noah Massengo and Hjalmar Ekdal are doubtful.

Prediction: 0-2

Wolverhampton Wanderers v Arsenal (3.30pm)

Matheus Cunha scored twice in Wolves’ away draw to West Midlands rivals Nottingham Forest.

Pedro Neto and Leon Chiwome are out with hamstring and ankle injuries, while Jean-Ricner Bellegarde and Rayan Ait-Nouri are doubtful with knee and hamstring injuries.

Arsenal were beaten by Aston Villa to miss an opportunity to return to the summit of the league table on Sunday. Jurrien Timber is out with a knee injury, while Martin Odegaard is doubtful.

Prediction: 1-2

Sunday

Everton v Nottingham Forest (9.30am)

Everton are just two points above the relegation zone after a humbling 6-0 defeat at Chelsea on Monday. Dele Alli and Lewis Dobbin are out with groin and ankle injuries, while Jarrad Branthwaite, Seamus Coleman, Nathan Patterson, Idrissa Gueye and Dominic Calvert-Lewin are doubtful.

Nottingham Forest squandered a second-half lead when settling for a home draw with Wolves last week and they have Willy Boly and Taiwo Awoniyi out this weekend.

Prediction: 1-0

Aston Villa v Bournemouth (11am)

Aston Villa must build on their morale-boosting upset win away to Arsenal, during which forward Ollie Watkins tied the club record for most goals (19) in a single campaign. Douglas Luiz serves the second match of his suspension for yellow-card accrual, with Tyrone Mings, Emiliano Buendia, Boubacar Kamara and Jacob Ramsey out to injury.

Bournemouth missed several chances in the home draw with Manchester United. Ryan Fredericks, Marcus Tavernier and Antoine Semenyo are out this week, while Chris Mepham, Tyler Adams and Luis Sinisterra are doubtful.

Prediction: 2-1

Crystal Palace v West Ham United (11am)

Crystal Palace started the upsets last week with victory over Liverpool at Anfield. Sam Johnstone, Rob Holding, Marc Guehi, Chris Richards, Cheick Doucoure and Matheus Franca are out with injury ande Jesurun Rak-Sakyi is doubtful.

West Ham lost at home to Fulham and missed a chance to jump into the top six. Alphonse Areola, Konstantinos Mavropanos, Kalvin Phillips and Jarrod Bowen are doubtful this weekend.

Prediction: 0-2

Fulham v Liverpool (12.30pm)

Fulham are moving up the table following the away win over London rivals West Ham and have no new injury concerns this week.

Liverpool lost the chance to climb to the summit of the table with the home loss to Palace. Joel Matip, Thiago Alcantara and Ben Doak are out through injury and Conor Bradley is doubtful with an ankle knock.

Prediction: 2-1