Erling Haaland could have bumper final day against West Ham
Fantasy managers have one final chance to adapt their squads and Manchester City striker Erling Haaland and Crystal Palace winger Michael Olise are strong options at either end of the price spectrum for the final day.
Andrew Shaw leads the overall standings in The Royal Gazette competition by 16 points from Jaylen Martin, while Zicco Pearman leads the May table with a tally of 244 points.
All matches take place at midday Bermuda time on Sunday
Arsenal v Everton
Arsenal must win to stand a chance of their first league title in 20 years and Bukayo Saka is doubtful for their final match.
Everton won their last home match at Goodison Park over Sheffield United last weekend. Vitaliy Mykolenko, Dele Alli and Nathan Patterson are out to various injuries this match, while Jack Harrison and Andre Gomes are doubtful.
Prediction: 3-1
Brentford v Newcastle United
Yoane Wissa scored a stoppage-time winner to lead Brentford to a win over Bournemouth last time out. Rico Henry, Aaron Hickey, Ben Mee and Josh DaSilva are out through injury this weekend, while Nathan Collins and Frank Onyeka are doubtful .
Newcastle have scored in all 19 Premier League home games for the first time in club history, marking the feat with Anthony Gordon’s equaliser against Brighton. Sven Botman, Jamaal Lascelles, Matt Targett, Joe Willock and Lewis Miley are out through injury, while Fabian Schar is doubtful.
Prediction: 2-3
Brighton & Hove Albion v Manchester United
Brighton have struggled in the final weeks of the season. Pervis Estupinan, Jan Paul van Hecke, Solly March, James Milner, Kaoru Mitoma, Jack Hinshelwood and Evan Ferguson are unavailable, while Joel Veltman is doubtful.
Manchester United will have one eye on the FA Cup final against Manchester City next weekend. Harry Maguire, Tyrell Malacia and Luke Shaw are out of this final league match, while Victor Lindelof, Raphael Varane, Mason Mount and Anthony Martial are doubtful.
Prediction: 0-2
Burnley v Nottingham Forest
Burnley were officially relegated with defeat at Tottenham Hotspur and Ameen Al-Dakhil, Jordan Beyer, Nathan Redmond, Luca Koleosho and Aaron Ramsey will miss their last Premier League match.
Nottingham Forest are all but safe and can guarantee Premier League survival with a point. Neco Williams is doubtful with a muscle injury this week.
Prediction: 2-2
Chelsea v Bournemouth
Chelsea are unbeaten in 13 league games after victory at Brighton on Wednesday. Reece James is suspended after being sent off in that match, while Wesley Fofana, Enzo Fernandez and Romeo Lavia are out through injury. Robert Sanchez, Ben Chilwell and Carney Chukwuemeka are doubtful to lack of fitness.
Bournemouth have their highest top-flight points tally despite being beaten at home by Brentford last week. Ryan Fredericks, Chris Mepham and Luis Sinisterra are out through injury this match, while Romain Faivre is doubtful.
Prediction: 2-1
Crystal Palace v Aston Villa
Crystal Palace cruised past Wolves, with Fantasy suggestion Olise scoring a goal and adding an assist. Naouirou Ahamada is suspended after being sent off in that match, while Cheick Doucoure, Jefferson Lerma and Matheus Franca are out injured. Rob Holding and Will Hughes are doubtful.
Villa will play Champions League football next season after their draw with Liverpool. Tyrone Mings, Emiliano Buendia, Boubacar Kamara and Jacob Ramsey are out to injury this match, while Alex Moreno, Matt Cash, Nicolo Zaniolo and Morgan Rogers are doubtful.
Prediction: 3-3
Liverpool v Wolverhampton Wanderers
Liverpool failed to hang on to a two-goal cushion in the draw at Aston Villa on Monday. Joel Matip, Thiago Alcantara and Ben Doak are unavailable, while Diogo Jota and Andy Robertson are doubtful.
Wolves were beaten by Crystal Palace despite Matheus Cunha scoring his twelfthth goal of the season. Craig Dawson, Pedro Neto and Leon Chiwome are missing for this match.
Prediction: 3-1
Luton Town v Fulham
Luton must winn by at least six goals and hope that Forest lose if they are to survive. Amari Bell, Tom Lockyer, Issa Kabore, Marvelous Nakamba and Jacob Brown are out through injury and illness, while Mads Juel Andersen, Dan Potts and Ross Barkley are doubtful.
Fulham will finish the season with just one win in their final nine games if they lose at Kenilworth Road. Issa Diop is suspended after being sent off against Manchester City, while Sasa Lukic is out with a calf injury this week.
Prediction: 1-2
Manchester City v West Ham United
Manchester City know a win will guarantee them the title, but goalkeeper Ederson is out after suffering a head injury in the midweek game against Tottenhham. Kevin de Bruyne is a doubt with a muscle.
West Ham have faltered in the quest for Europe with just one win from their last five games. Kalvin Phillips is ineligible to face his parent club to league loan rules, while Nayef Aguerd and Konstantinos Mavropanos are out through injury.
Prediction: 3-0
Sheffield United v Tottenham
Sheffield United have conceded the most goals of any team in a single Premier League campaign.
George Baldock, Chris Basham, Rhys Norrington-Davies and Oliver McBurnie are out injured, while John Egan, Tom Davies, Ben Osborn and Daniel Jebbison are doubtful.
Spurs were defeated at home by City to extinguish their Champions League hopes. Fraser Forster, Ben Davies, Ryan Sessegnon, Destiny Udogie, Yves Bissouma, Richardson, Manor Solomon and Timo Werner are out with injury.
Prediction: 0-5